An AChE inhibitor
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

AChE-IN-26 (bromide)

Item No. 46466

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(3,4-dimethoxybenzoyl)amino]-1-(phenylmethyl)-pyridinium, monobromide
CAS Number
2977170-10-6
Synonyms
  • Acetylcholinesterase-IN-26
  • Acetylcholinesterase Inhibitor 26
  • AChE Inhibitor 26
Molecular Formula
C21H21N2O3 • Br
Formula Weight
429.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
COC1=CC(C(NC(C=C2)=CC=[N+]2CC3=CC=CC=C3)=O)=CC=C1OC.[Br-]
InChi Code
InChI=1S/C21H20N2O3.BrH/c1-25-19-9-8-17(14-20(19)26-2)21(24)22-18-10-12-23(13-11-18)15-16-6-4-3-5-7-16;/h3-14H,15H2,1-2H3;1H
InChi Key
VGTPSQFSPGENRA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $29

    Add

    5 mg

    $65

    Add

    10 mg

    $116

    Add
    Product Description

    AChE-IN-26 is an inhibitor of acetylcholinesterase (AChE; IC50 = 0.42 µM).1 It is selective for AChE over butyrylcholinesterase (BChE) at 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Abdullaha, M., Nuthakki, V.K., and Bharate, S.B. Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur. J. Med. Chem. 207, 112761 (2020).