A membrane-labeling probe
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pGk13a (trifluoroacetate salt)

Item No. 46578

Technical Information
Formal Name
N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S)-4,7,10,13,16,19,22,25,28,31,34,37-dodecakis(4-aminobutyl)-44-azido-40-carbamoyl-2,5,8,11,14,17,20,23,26,29,32,35,38-tridecaoxo-3,6,9,12,15,18,21,24,27,30,33,36,39-tridecaazatetratetracontyl)palmitamide, trifluoroacetate salt
Synonyms
  • Palmitoyl-glycine-(D-lysine)13-azide
Molecular Formula
C96H190N30O15 • XCF3COOH
Formula Weight
Purity
≥95%
A solid
Peptide Sequence
palmitoyl-Gkkkkkkkkkkkk-(k-azide)-NH2
DMSO: Sparingly soluble: 1-10 mg/mlWater: Sparingly soluble: 1-10 mg/ml
SMILES
CCCCCCCCCCCCCCCC(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN=[N+]=[N-])C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C96H190N30O15.C2HF3O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-54-82(127)111-68-83(128)113-70(42-15-28-55-97)85(130)115-72(44-17-30-57-99)87(132)117-74(46-19-32-59-101)89(134)119-76(48-21-34-61-103)91(136)121-78(50-23-36-63-105)93(138)123-80(52-25-38-65-107)95(140)125-81(53-26-39-66-108)96(141)124-79(51-24-37-64-106)94(139)122-77(49-22-35-62-104)92(137)120-75(47-20-33-60-102)90(135)118-73(45-18-31-58-100)88(133)116-71(43-16-29-56-98)86(131)114-69(84(109)129)41-27-40-67-112-126-110;3-2(4,5)1(6)7/h69-81H,2-68,97-108H2,1H3,(H2,109,129)(H,111,127)(H,113,128)(H,114,131)(H,115,130)(H,116,133)(H,117,132)(H,118,135)(H,119,134)(H,120,137)(H,121,136)(H,122,139)(H,123,138)(H,124,141)(H,125,140);(H,6,7)/t69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-;/m0./s1
InChi Key
VYUNPNVNBSHREE-KBEXUQNBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    pGk13a is a membrane-labeling probe.1 It contains palmitic acid (Item Nos. 10006627 | 43561), which acts as a membrane anchor, conjugated to a poly-D-lysine peptide, which acts as a hydrogel anchor during chemical softening, and an azide group that can be conjugated to fluorophores via click chemistry. It has been used in ultrastructural membrane expansion microscopy (umExM) to increase the resolution of confocal microscopy to approximately 60 nm, allowing for the visualization of membranous structures, proteins, and RNA, segmentation of neuronal compartments, and tracing of axons in mouse brain slices.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shin, T.W., Wang, H., Zhang, C., et al. Dense, continuous membrane labeling and expansion microscopy visualization of ultrastructure in tissues. Nat. Commun. 16(1), 1579 (2025).