Prostaglandin D2-MOX Express ELISA Kit | Cayman Chemical
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Prostaglandin D2-MOX Express ELISA Kit

Item № 500151
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 solid wells $270.00 0.00
     96 strip wells $270.00 0.00
     480 solid wells $1,013.00 0.00
     480 strip wells $1,013.00 0.00

Pricing updated 2018-11-14. Prices are subject to change without notice.

Description
Features
  • Treatment of samples with MOX hydrochloride converts unstable PGD2 to stable PGD2-MOX; MOX derivatization reagent included with assay
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure PGD2-MOX levels down to 16 pg/ml
  • Rapid assay; get results in under 4 hours
Synonyms
  • PGD2-MOX Express EIA Kit

Prostaglandin D2 (PGD2) is biosynthesized in the brain by a lipocalin-type PGD2 synthase where it acts in the CNS to promote sleep induction and lowering of body temperature.1 PGD2 is also the major eicosanoid product of mast cells and is synthesized in large quantities by a hematopoetic-type PGD synthase during allergic and asthmatic anaphylaxis.2,3 Measurement of the parent eicosanoid PGD2 is appropriate in the supernatants of cell cultures, where PGD2 levels may reach several ng/ml, and in CSF, where concentrations of several hundred pg/ml have been measured.4 Cayman Chemical’s PGD2-MOX Express ELISA is a competitive assay that permits the rapid measurement of PGD2 from biological samples, requiring only 1 hour incubation and development times for each step. The methodology for the assay is the same as that employed in Cayman’s widely utilized PGD2-MOX ELISA (Item No. 512011). While Item No. 512011 offers superior sensitivity (80% B/B0 ~3.1 pg/ml), the new PGD2-MOX Express EIA offers the convenience of a fast assay while still achieving an 80% B/B0 ~16 pg/ml and an assay range of 7.8-1,000 pg/ml.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • PGD2-MOX Express EIA Kit
Assay Range
7.8-1,000 pg/ml
Sensitivity
80% B/B0: 16 pg/ml
Mid-point
50% B/B0: 60-100 pg/ml
Cross Reactivity
  • (tetranor-PGEM) <0.01%
  • (tetranor-PGFM) <0.01%
  • (Prostaglandin D2-mox) 100%
Show all 5

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Abbreviated Kit Protocol

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Hayaishi, O. Sleep-wake regulation by prostaglandins D2 and E2 J. Biol. Chem. 263(29), 14593-14596 (1988).

2. Mahmud, I., Ueda, N., Yamaguchi, H., et al. Prostaglandin D synthase in human megakaryoblastic cells The Journal of Biological Chemisty 272, 28263-28266 (1997).

3. Matsuoka, T., Hirata, M., Tanaka, H., et al. Prostaglandin D2 as a mediator of allergic asthma Science 287, 2013-2017 (2000).

4. Ram, A., Pandey, H.P., Matsumura, H., et al. CSF levels of prostaglandins, especially the level of prostaglandin D2, are correlated with increasing propensity towards sleep in rats Brain Research 751, 81-89 (1997).

Technical Support

All 480 well kits are supplied with a single 500 dtn vial of antiserum and tracer, or Fab' conjugate that must be used within the stated time following reconstitution.

Analysis Tools

View our analysis workbook for Prostaglandin D2-MOX Express ELISA Kit

View all analysis workbooks

View the pre-configured analysis tool for Prostaglandin D2-MOX Express ELISA Kit on MyAssays.com

Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
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You may be eligible to receive a free sample of Prostaglandin D2-MOX Express ELISA Kit under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640