A competitive assay used for quantification of CysLT
Features
  • Detect all CysLTs (LTC4, LTD4, and LTE4) in urine and other sample matrices
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure CysLT levels down to 40.5 pg/ml
  • Incubation: 18 hours | Development: 90-120 minutes | Read: Colorimetric at 405-420 nm
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Cysteinyl Leukotriene ELISA Kit

Item No. 500390

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • CysLT EIA Kit
Assay Range
8.6-2,500 pg/ml
Sensitivity
80% B/B0: 40.5 pg/ml
Cross Reactivity
(Leukotriene C4) 100%(Leukotriene D4) 100%(Leukotriene E4) 79%(5,6-DiHETE) 3.7%(Leukotriene B4) 1.3%(5(S)-HETE) 0.04%(Arachidonic Acid) <0.01%
Origin
Animal/Bovine, Animal/Eel, Animal/Mouse
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 solid wells

    $428

    Add

    96 strip wells

    $428

    Add

    480 solid wells

    $1,605

    Add

    480 strip wells

    $1,605

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid via the 5-lipoxygenase (5-LO) pathway in leukocytes. LTC4, LTD4, and LTE4 are collectively referred to as cysteinyl leukotrienes (CysLTs). LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. The biological activity of LTE4 is much lower in most systems studied, but its presence reflects the prior existence of LTC4 and LTD4. Cayman’s CysLT ELISA Kit is a competitive assay based on a proprietary high-affinity monoclonal antibody that can be used for quantification of CysLT in urine and other sample matrices. The assay has a range from 8.6-2,500 pg/ml and a sensitivity (80% B/B0) of approximately 40.5 pg/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Mummy, D.G., McIntosh, M.J., Carey, K.J., et al. A method for MRI-guided bronchoscopy to identify obstructed airway segments. Physiol. Rep. 13(4), e70119 (2025).

    Gan, P.X.L., Liao, W., Lim, H.F., et al. Dexamethasone protects against Aspergillus fumigatus-induced severe asthma via modulating pulmonary immunometabolism. Pharmacol. Res. 196, 106929 (2023).

    Ualiyeva, S., Lemire, E., Aviles, E.C., et al. Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation. Sci. Immunol. 6(66), eabj0474 (2021).

    Pundir, P., Liu, R., Vasavda, C., et al. A connective tissue mast-cell-specific receptor detects bacterial quorum-sensing molecules and mediates antibacterial immunity. Cell Host Microbe 26, 114-122 (2019).