An immunometric assay for the measurement of type II collagen antibody in plasma and serum
Features
  • Measure mouse anti-bovine type II collagen IgG in mouse plasma or serum
  • Employs an affinity-purified anti-CII polyclonal antibody standard isolated from mice with collagen-induced arthritis
  • Assay Range: 15.6-1,000 U/ml with an LLOQ of 15.6 U/ml
  • Rapid assay; get results in under 4 hours
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Mouse Anti-Type II Collagen IgG Assay Kit (bovine)

Item No. 500410

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Assay Range
15.6-1,000 U/ml
Lower Limit of Quantification
15.6 U/ml
Origin
Animal/Bovine, Animal/Donkey, Animal/Mouse
Shipping & Storage Information
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    96 wells

    $416

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    Product Description

    Collagen-induced arthritis (CIA) is an experimental autoimmune disease that is widely used as a model of human rheumatoid arthritis (RA) in the study of the pathogenic mechanisms of this disease and for testing potential therapeutics. Circulating levels of anti-type II collagen antibody are strongly associated with the development of arthritis and can be used as a biomarker of CIA. Cayman’s Mouse Anti-Type II Collagen IgG Assay is an immunometric (i.e., sandwich) assay which can be used to measure anti-type II collagen antibody in plasma or serum without prior sample purification. This kit uses a bovine collagen-coated plate and an affinity-purified polyclonal antibody isolated from mice with CIA as a standard. This standard provides the most accurate measurement of anti-CII concentration in experimental plasma samples. One unit of standard in this assay is approximately equal to 1 ng of IgG protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 15.6 U/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.