For the quantification of aldosterone in serum, plasma, urine, and other sample matrices
Features
  • Measure aldosterone, the principle mineralocorticoid controlling sodium and potassium balance
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure aldosterone levels down to 30 pg/ml
  • Incubation: 18 hours | Development: 90-120 minutes | Read: Colorimetric at 405-420 nm
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Aldosterone ELISA Kit

Item No. 501090

Technical Information
Synonyms
  • Aldosterone EIA
Assay Range
15.6-2,000 pg/ml
Sensitivity
80% B/B0: 30 pg/ml
Cross Reactivity
(Aldosterone) 100%(3β,5β-Tetrahydroaldosterone) 41%(3α,5β-Tetrahydroaldosterone) 0.5457%(Corticosterone) 0.1051%(Progesterone) 0.0360%(Pregnenolone) 0.0243%(Androstenedione) 0.0212%(11-Deoxycorticosterone) 0.0166%(Testosterone) 0.0072%(17-Hydroxypregnenolone) 0.0027%(17-Hydroxyprogesterone) 0.0013%(11-Deoxycortisol) 0.0008%(DHEA) 0.0008%(Cortisol) 0.0006%(Cortisone) 0.0006%(DHEA Sulfate) 0.0005%(5α-Dihydrotestosterone) 0.0004%(Estrone) 0.0001%(Dexamethasone) <0.01%(β-Estradiol) <0.01%(Estriol) <0.01%(Estrone Sulfate) <0.01%
Origin
Animal/Bovine, Animal/Eel, Animal/Mouse, Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    Aldosterone, a steroid hormone secreted by the adrenal cortex, is the principle mineralocorticoid controlling sodium and potassium balance. Serum aldosterone levels in normal upright adult individuals are generally less than 300 pg/ml. Only a fraction of urinary aldosterone is excreted intact, thus urinary excretion of aldosterone in normal adults is typically assessed as a combination of free aldosterone and aldosterone-18-glucuronide and is generally less than 20 µg/24 hr. Cayman's Aldosterone ELISA Kit is a competitive assay that can be used for quantification of aldosterone in serum, plasma, urine, and other sample matrices. The assay has a range from 15.6-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 30 pg/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Koike, T., Yoshikawa, M., Ando, H.K., et alDiscovery of soticlestat, a potent and selective inhibitor for cholesterol 24-hydroxylase (CH24H). J. Med. Chem. 64(16), 12228-12244 (2021).

    Antolic, A., Feng, X., Wood, C.E., et alIncreased maternal nighttime cortisol concentrations in late gestation alter glucose and insulin in the neonatal lamb. Physiol. Rep. 3(9), e12548 (2015).