An ELISA for quantifying Annexin A1 in biological matrices
Features
  • Detect human annexin A1 in tissue culture media, serum, and plasma
  • Measure human annexin A1 levels down to 0.18 ng/ml
  • Assay up to 40 samples in duplicate per plate
  • Rapid assay; get results in under 5 hours
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Annexin A1 (human) ELISA Kit

Item No. 501550

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Limit of Detection
0.18 ng/ml
Assay Range
0.20-20 ng/ml
Sensitivity
0.2 ng/ml
Origin
Animal/Bovine, Animal/Mouse, Animal/Rabbit
Shipping & Storage Information
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 wells

    $504

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    Product Description

    Cayman’s Annexin A1 (human) ELISA Kit is a sandwich assay which can be used to measure human annexin A1 in tissue culture media, serum and plasma. The standard curve spans the range of 0.20 - 20 ng/ml. Annexin A1 is a natural anti-inflammatory protein produced by neutrophils and monocytes. The glucocorticoid-induced production and release of annexin A1 is the primary means by which glucocorticoids function as anti-inflammatory agents. Annexin A1 inhibits the synthesis of pro-inflammatory eicosanoids by suppressing the function of secretory phospholipase A2 (sPLA2). This, in turn, limits the recruitment of neutrophils into inflammatory sites and down-regulates the production of pro-inflammatory mediators by those neutrophils that enter inflammatory sites. Annexin A1 also functions in the resolution of inflammation by inducing neutrophil apoptosis, and promoting neutrophil clearance (efferocytosis) by macrophages. The pro-resolving functions of annexin A1 are mediated via binding to FPR2/ALX, a receptor it shares with the specific pro-resolving mediators lipoxin A4 (LXA4) and resolvin D1 (RvD1).

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.