A competitive ELISA for the detection or semi-quantification of SARS-CoV-2 neutralizing antibodies
Features
  • Qualitative and semi-quantitative assay for detecting neutralizing antibodies of the spike S1 RBD-ACE2 interaction
  • Validated with COVID-19-positive and -negative human samples
  • Rapid assay; get results in <4 hours
  • Run up to 44 samples in duplicate and 28 samples in triplicate
  • Plate-based colorimetric readout (450 nm)
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SARS-CoV-2 Neutralizing Antibody Detection ELISA Kit

Item No. 502070

Technical Information
Synonyms
  • Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Detection
Limit of Detection
19 ng/ml
Assay Range
7.8-1,000 ng/ml
Sensitivity
46 ng/ml
Origin
Animal/Bovine
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Cayman’s SARS-CoV-2 Neutralizing Antibody Detection ELISA Kit is a competitive assay that can be used for qualitative and/or semi-quantitative measurement of neutralizing antibodies in human plasma and serum. When using the neutralizing antibody standard provided in the kit, the assay has a range of 7.81-1,000 ng/ml with a midpoint of approximately 120 ng/ml (50% B/B0) and a sensitivity (80% B/B0) of approximately 46 ng/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Chupp, D.P., Rivera, C.E., Zhou, Y., et alA humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses. Nat. Immunol. 2024, 1489-1506 (2024).