A competitive ELISA for the quantification of 8-OHdG, 8-OHG, and 8-hydroxyguanine
Features
  • Measure major oxidative damage markers, 8-hydroxy-2’-deoxyguanosine, 8-hydroxyguanosine, and 8-hydroxyguanine in urine, cell culture medium, cell lysates, tissue samples, saliva, and plasma/serum samples
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Assay Range: 34.3-10,000 pg/ml
  • Incubation: 2 hours | Development: 60-90 minutes | Read: Colorimetric at 405-420 nm
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

DNA/RNA Oxidative Damage Express ELISA Kit

Item No. 502890

Kit Booklet (PDF)Validation Data (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • 8-hydroxy-2’-Deoxyguanosine
  • Deoxyribonucleic Acid
  • 8-Hydroxyguanosine
  • 8-OHdG
  • 8-OHG
  • Ribonucleic Acid
Limit of Detection
62 pg/ml
Assay Range
34.3-10,000 pg/ml
Origin
Animal/Bovine, Animal/Eel, Animal/Mouse
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 solid wells

    $688

    Add

    96 strip wells

    $688

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Cayman Chemical DNA/RNA Oxidative Damage Express Kit detects all three oxidized guanine/guanosine species; 8-OHdG from DNA, 8-OHG from RNA, and 8-hydroxyguanine from either DNA or RNA. Some commercial vendors offer immunoassays that detect only 8-OHdG, and not the other two molecules. The advantage of the Cayman kit is that it captures a more complete set of biologically relevant products of oxidative damage than do assays that are restricted to analysis of only 8-OHdG.

    However, because Cayman’s kit recognizes more than 8-OHdG, it is not valid to compare the results from the Cayman ELISA Kit to an LC/MS analysis of 8-OHdG. The ELISA value will always be significantly higher than LC/MS because the ELISA also detects 8-OHG and 8-hydroxyguanine.

    This express assay has a range from 34.3-10,000 pg/ml and a lower limit of detection (LLOD) of 62 pg/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.