An immunometric assay for the detection of angiotensin in human plasma
Features
  • Measure angiontensin II in mammalian plasma, serum, and cell culture supernatant samples
  • Assay 33 samples in duplicate
  • Incubations: 1 hour | Overnight
  • Angiotensin II Inhibitor Cocktail (Item No. 9000681) and SPE Cartridges (Phenyl) (Item No. 400048) are available for sample storage and clean up
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Angiotensin II EIA Kit

Item No. 589301

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Angiotensin II ELISA Kit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 wells

    $857

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    This product has been produced by

    Precellys
    Bioanalysis & Assay Development Services
    Your Vision. Our Expertise.
    • Bioanalysis and compound screening using Cayman or qualified commercial assay kits
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    Product Description

    Angiotensin II is a primary reactive vasoconstrictor, the main stimulus for aldosterone release, and one of the causative factors of chronic hypertension. The active angiotensin II octapeptide is released via a tightly controlled series of prohormones and proteases as diagrammed below. Normal human plasma angiotensin II levels are from 10-30 pg/ml when measured at rest in the supine position; they increase on standing, exercise, dehydration, or sodium depletion. The unique, patented 'Immobilized Antigen' technology of this angiotensin II immunometric assay allows reliable detection of 1-2 pg/ml, or as little as 10% of the normal human plasma concentration. [Bertin Catalog No. A05880]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Tufiño, C., Villanueva-López, C., Ibarra-Barajas, M., et al. Experimental gestational diabetes mellitus induces blunted vasoconstriction and functional changes in the rat aorta. Biomed. Res. Int. 329634 (2014).

    Carroll, W.X., Kalupahana, N.S., Booker, S.L., et al. Angiotensinogen gene silencing reduces markers of lipid accumulation and inflammation in cultured adipocytes. Front. Endocrinol. (Lausanne) 4, 10 (2013).

    Marampon, F., Gravina, G.L., Scarsella, L., et al. Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis. J. Hypertens. 31(10), 1972-1983 (2013).

    Ye, M., Wysocki, J., Gonzalez-Pacheco, F.R., et al. Murine recombinant ACE2: Effect on angiotensin II-dependent hypertension and distinctive ACE2 inhibitor characteristics on rodent and human ACE2. Hypertension 60(3), 730-740 (2012).

    Hammerschmidt, S., Kuhn, H., Gessner, C., et al. Stretch-induced alveolar type II cell apoptosis: Role of endogenous bradykinin and PI3K-Akt signaling. Am. J. Respir. Cell Mol. Biol. 37(6), 699-705 (2007).