Histamine EIA Kit | Cayman Chemical
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Histamine EIA Kit

Item № 589651
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     96 wells $530.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

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  • Measure histamine in plasma, serum, bronchoalveolar lavage, tissue extracts, and cell culture supernatant samples
  • Assay 33 samples in duplicate
  • Incubation: Overnight
  • 1H-imidazole 4-ethaneamine ELISA Kit

Histamine (1H-imidazole 4-ethaneamine) is a component of the storage granules of myeloid cells including basophils1 and mast cells.2 Histamine secretion from gastric serosal cells contributes to the stimulation of gastric acid secretion. The clinical importance of histamine in the pathogenesis of allergy and asthma has long been appreciated.3 Together with the cysteinyl-leukotrienes, histamine contributes to the airway constriction, edema, vascular congestion, and inflammatory cell recruitment seen in acute allergic respiratory disease. Bacterial decarboxylation of the amino acid histidine in fresh fish produces histamine, which can be used as a health hazard biomarker indicative of bacterial contamination. The measurement of histamine levels is therefore of importance in fields as diverse as food quality inspection, pharmaceutical development, and clinical diagnostics. Our Histamine EIA kit is a derivitization-amplified competitive enzyme immunoassay which detects histamine within the range from 400 pg/ml to 50,000 pg/ml. The assay can be used for the analysis of histamine in blood (plasma or serum) without extraction or purification. The use of other sample types may require further processing or purification of the sample. [Bertin Catalog No. A05890]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
  • 1H-imidazole 4-ethaneamine ELISA Kit
  • (100%) Histamine
  • (0.04%) 3 methyl Histamine
  • (0.01%) 1 methyl Histamine
Show all 5

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 18 months
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Peters, S.P., Kagey-Sobotka, A., MacGlashan, D.W., Jr., et al. Effect of prostaglandin D2 in modulating histamine release from human basophils Journal of Pharmacology and Experimental Therapeutics 228, 400-406 (1984).

2. Naclerio, R.M., Hubbard, W., Lichtenstein, L.M., et al. Clinical aspects of allergic disease. Origin of late phase histamine release Journal of Allergy and Clinical Immunology 98, 721-723 (1996).

3. Sydbom, A., Kumlin, M., and Dahlén, S.E. Stimulus-dependence and time-course of histamine and leukotriene release from chopped and dispersed human lung tissue Agents and Actions 20, 198-201 (1987).

Technical Support
Analysis Tools

View our analysis workbook for Histamine EIA Kit

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Ann Arbor, Michigan 48108 USA

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