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Neutrophil Myeloperoxidase Activity Assay Kit

Item № 600620
product image
     2 x 96 wells $310.00 0.00

Pricing updated 2019-06-15. Prices are subject to change without notice.

  • Assay the release of enzymatically-active MPO from activated phagocytes
  • Utilizes TMB as a chromogenic substrate for MPO
  • Includes a specific inhibitor of MPO function to verify specificity
  • Includes reagents needed to isolate neutrophils from human whole blood
  • Neutrophil MPO

Myeloperoxidase (MPO), released from neutrophils to degrade invading pathogens, provides one of the earliest lines of defense in innate immunity. It catalyzes the hydrogen peroxide-mediated oxidation of halide ions to products such as hypochlorous acid (HOCl). These reactive products participate in a variety of secondary reactions which in turn lead to modifications of proteins and destruction of the extracellular matrix. Cayman’s Neutrophil Myeloperoxidase Activity Assay kit utilizes 3,3',5,5'-tetramethyl-benzidine (TMB) as a chromogenic substrate, which upon reacting with MPO, yields a blue color detectable by its absorbance at 650 nm. The color intensity is proportional to the amount of MPO in the sample. Reagents needed to isolate neutrophils from whole blood are included in the kit, as is PMA, which is known to stimulate MPO release from neutrophils. A specific inhibitor for MPO, 4-aminobenzhydrazide (ABH), is also included in the kit for verifying the specificity of the assay.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
  • Neutrophil MPO

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 6 months
Downloads & Resources
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Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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