Derivatization Kit for the sensitive LC-MS/MS analysis of dienes such as Vitamin D and Vitamin D metabolites
Features
  • The intended purpose of this kit is to enhance sensitivity of 1,3 conjugated dienes (e.g. vitamin D metabolites) in mass spectrometry applications using an optimized derivatizion reagent
  • This kit includes a derivatization reagent specific for 1,3 dienes, a Vitamin D3 control standard, and instructions for use
  • This kit has been shown to enhance detection limits of Vitamin D3 by an order of magnitude relative to direct analysis and up to 5-fold over competitor products
  • Improved detection leads to increased precision and accuracy in quantitative mass spectrometry applications
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Dienes Derivatization MaxSpec® Kit

Item No. 601510

Technical Information
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    This Dienes Derivatization MaxSpec® Kit is designed for the sensitive, accurate detection and quantitation of diene-containing compounds such as Vitamin D or Vitamin D metabolites. This is achieved through chemical derivatization utilizing a Derivatization Reagent based upon click chemistry. Included in this kit is a simple, rapid, and efficient protocol to extract and derivatize diene compounds from biological matrices. The resulting mixture reduces ion suppression and increases sensitivity with detection limits of 10-100 pM in most sample matrices. This extraction protocol is based upon protein precipitation and solid phase extraction (SPE) using the Dienes Derivatization MaxSpec® Kit and Waters HLB cartridges. After drying under vacuum, the extracted and concentrated diene compounds are directly dissolved in Derivatization Solution. The final mixture can be directly injected into an LC-MS/MS.

    WARNING This product is not for human or veterinary use.