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Arachidonate 15-Lipoxygenase (soybean) - Purified

Item No. 60700

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • 13-S-Lipoxygenase-1
  • 15-Lipoxygenase
  • Lipoxygenase Lx3
Purity
≥50% estimated by SDS-PAGE
Source
Soybeans (Provar)
MW
94 and 97 kDa
Formulation (Request formulation change)
100 mM Tris, pH 7.0, 10% glycerol
UniProt Accession №
B3TDK6, P08170
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    5 Munits

    $528

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    Product Description

    This product contains primarily 13S-lipoxygenase-1 and lipoxygenase Lx3 which are non-heme, non-sulfur ferroproteins, that are 94 and 97 kDa, respectively.13-S-Lipoxygenase is referred to as a type-1 enzyme and exhibits maximum catalytic activity at pH 9.0.1,2 The substrate specificity of this product is linoleate>arachidonate>eicosapentaenoate.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Funk, M.O., Carroll, R.T., Thompson, J.F., et al. The lipoxygenases in developing soybean seeds, their characterization and synthesis in vitro. Plant Physiol. 82, 1139-1144 (1986).

    2. Draheim, J.E., Carroll, R.T., McNemar, T.B., et al. Lipoxygenase isoenzymes: A spectroscopic and structural characterization of soybean seed enzymes. Arch. Biochem. Biophys. 269, 208-218 (1989).

    Product Citations

    Hinman, A., Holst, C.R., Latham, J.C., et al. Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase. PLoS One 13(8), e0201369 (2018).