A PAF analog that contains docosahexaenoate
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1-O-hexadecyl-2-Docosahexaenoyl-sn-glycero-3-PC

Item No. 60903

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-O-hexadecyl-2-O-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glyceryl-3-phosphorylcholine
CAS Number
132213-85-5
Synonyms
  • 1-O-hexadecyl-2-Docosahexaenoyl-sn-glycero-3-phosphocholine
  • 1-O-hexadecyl-2-Docosahexaenoyl-sn-glycero-phosphocholine
  • 1-O-hexadecyl-2-Docosahexaenoyl-sn-glyceryl-phosphocholine
  • 1-O-hexadecyl-2-O-Docosahexaenoyl-sn-glycero-PC
  • 1-O-hexadecyl-2-O-Docosahexaenoyl-sn-glyceryl-PC
  • PC(O-16:0/22:6)
Molecular Formula
C46H82NO7P
Formula Weight
792.1
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol containing 0.1% BHT
Solubility(Learn about Variance in Solubility)
acidic PBS: <50 ug/mlbasic PBS: <50 ug/mlDMF: >14.3 mg/mlDMSO: >2.5 mg/mlEthanol: >1.7 mg/mlPBS pH 7.2: <50 ug/ml
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C46H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-26-27-29-31-33-35-37-39-46(48)54-45(44-53-55(49,50)52-42-40-47(3,4)5)43-51-41-38-36-34-32-30-28-21-19-17-15-13-11-9-7-2/h8,10,14,16,20,22,24-25,27,29,33,35,45H,6-7,9,11-13,15,17-19,21,23,26,28,30-32,34,36-44H2,1-5H3/b10-8-,16-14-,22-20-,25-24-,29-27-,35-33-/t45-/m1/s1
InChi Key
QQQQNYAHSSIZBU-HIQXTUQZSA-N
Side Chain Carbon Sum
38:6
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $65

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    5 mg

    $244

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    10 mg

    $455

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    Product Description

    1-O-hexadecyl-2-Docosahexaenoyl-sn-glycero-3-PC is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. 1-O-hexadecyl-2-Docosahexaenoyl-sn-glycero-3-PC can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tanaka, T., Iimori, M., Tsukatani, H., et al. Platelet-aggregating effects of platelet-activating factor-like phospholipids formed by oxidation of phosphatidylcholines containing an sn-2-polyunsaturated fatty acyl group. Biochim. Biophys. Acta 1210, 202-208 (1994).

    2. Tanaka, T., Tokumura, A., and Tsukatani, H. Platelet-activating factor (PAF)-like phospholipids formed during peroxidation of phosphatidylcholines from different foodstuffs. Biosci. Biotechnol. Biochem. 59, 1389-1393 (1995).