The product of acylation of lyso-PAF C-16
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1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC

Item No. 60904

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-O-hexadecyl-2-O-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glyceryl-3-phosphorylcholine
CAS Number
86288-11-1
Synonyms
  • Arachidonoyl PAF C-16
  • 1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine
  • PC(O-16:0/20:4)
Molecular Formula
C44H82NO7P
Formula Weight
768.1
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol containing 0.1% BHT
Solubility(Learn about Variance in Solubility)
acidic PBS: 0.5 mg/mlbasic PBS: 0.5 mg/mlDMF: 10 mg/mlDMSO: 2 mg/mlEthanol: 1 mg/mlPBS pH 7.2: 0.5 mg/ml
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C44H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-44(46)52-43(42-51-53(47,48)50-40-38-45(3,4)5)41-49-39-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h14,16,20,22,24-25,29,31,43H,6-13,15,17-19,21,23,26-28,30,32-42H2,1-5H3/b16-14-
InChi Key
DUUSFCFZBREELS-WWBBCYQPSA-N
Side Chain Carbon Sum
36:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $62

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    5 mg

    $252

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    10 mg

    $472

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    25 mg

    $956

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    Product Description

    1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC is the product of acylation of lyso-PAF C-16 (Item No. 60906) by a CoA-independent transacylase.1,2 It is the most common precursor for formation of PAF C-16 (Item No. 60900) by the remodeling pathway.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kramer, R.M., Patton, G.M., Pritzker, C.R., et al. Metabolism of platelet-activating factor in human platelets. The Journal of Biological Chemisty 259, 13316-13320 (1984).

    2. Venable, M.E., Olson, S.C., Nieto, M.L., et al. Enzymatic studies of lyso platelet-activation factor acylation in human neutrophils and changes upon stimulation. The Journal of Biological Chemisty 268(11), 7965-7975 (1993).

    3. Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M. Platelet-activating factor. The Journal of Biological Chemisty 265(29), 17381-17384 (1990).