An analog of DAG
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Hexadecyl Acetyl Glycerol

Item No. 60920

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-O-hexadecyl-2-O-acetyl-sn-glycerol
CAS Number
77133-35-8
Synonyms
  • HAG
Molecular Formula
C21H42O4
Formula Weight
358.6
Purity
≥95% (as a 9:1 mixture of the 2-acetyl and 1-acetyl)
Formulation (Request formulation change)
A 25 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMSO: 10 mg/mlEthanol: MisciblePBS (pH 7.2): 0.1 mg/ml
SMILES
CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)C
InChi Code
InChI=1S/C21H42O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24-19-21(18-22)25-20(2)23/h21-22H,3-19H2,1-2H3/t21-/m0/s1
InChi Key
QTEHGUUSIIWOOW-NRFANRHFSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    5 mg

    $61

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    10 mg

    $116

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    25 mg

    $258

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    50 mg

    $455

    Add
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    Product Description

    Hexadecyl acetyl glycerol (HAG) is an analog of DAG, which inhibits the activation of PKC by DAG.1 It also inhibits the growth of HL-60 cells and induces differentiation to cells resembling mononuclear phagocytes. Following treatment with 5 µg/ml HAG for six days, HL-60 cells demonstrated a 10-fold increase in non-specific esterase activity.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Daniel, L.W., Small, G.W., and Schmitt, J.D. Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols. Biochem. Biophys. Res. Commun. 151, 291-297 (1988).

    2. McNamara, M.J.C., Schmitt, J.D., Wykle, R.L., et al. 1-O-Hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells. Biochem. Biophys. Res. Commun. 122, 824-830 (1984).