A potent PPARγ agonist
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Azelaoyl PAF

Item No. 60924

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-O-hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
CAS Number
354583-69-0
Molecular Formula
C33H66NO9P
Formula Weight
651.9
Purity
≥95%
Formulation
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 33 mg/mlDMSO: 8 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
CCCCCCCCCCCCCCCCOC[C@@H](OC(CCCCCCCC(O)=O)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChi Code
InChI=1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
InChi Key
ZDFOCDTXDPKJKA-WJOKGBTCSA-N
Side Chain Carbon Sum
25:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $83

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    1 mg

    $158

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    5 mg

    $455

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    Product Description

    Azelaoyl PAF is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-Δ12,14-prostaglandin J2, and equipotent with rosiglitazone as a ligand for this receptor.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Davies, S.S., Pontsler, A.V., Marathe, G.K., et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. The Journal of Biological Chemisty 276(19), 16015-16023 (2001).