An analog of oleic acid
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Oleyl Trifluoromethyl Ketone

Item No. 62640

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1,1-trifluoro-10Z-nonadecen-2-one
CAS Number
177987-23-4
Synonyms
  • Heptadecyl Trifluoromethyl Ketone
  • OTK
Molecular Formula
C19H33F3O
Formula Weight
334.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/ml (from ATK)DMSO: 25 mg/ml (from ATK)PBS pH 7.2: 50 µg/ml (from ATK)
SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)C(F)(F)F
InChi Code
InChI=1S/C19H33F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(23)19(20,21)22/h9-10H,2-8,11-17H2,1H3/b10-9-
InChi Key
SOJGXPSMVNTNQL-KTKRTIGZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $16

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    5 mg

    $59

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    10 mg

    $98

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    50 mg

    $423

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    Product Description

    Oleyl trifluoromethyl ketone is an analog of oleic acid (Item No. 90260) in which the COOH group is replaced by trifluoromethyl ketone. It is a potent inhibitor of FAAH, in both human and rat. In transfected COS-7 cells, 10 µM oleyl trifluoromethyl ketone inhibits 95.7% of human FAAH activity and 94.8% of rat FAAH activity.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cravatt, B.F., Giang, D.K., Mayfield, S.P., et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384(6604), 83-87 (1996).

    2. Giang, D.K., and Cravatt, B.F. Molecular characterization of human and mouse fatty acid amide hydrolases. Proc. Natl. Acad. Sci. USA 94, 2238-2242 (1997).