An inositol phospholipid with possible roles in signal transduction
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PtdIns-(3)-P1 (1,2-dipalmitoyl) (ammonium salt)

Item No. 64921

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(1,2-dihexadecanoylphosphatidyl)inositol-3-phosphate, diammonium salt
Synonyms
  • DPPI-3-P
  • PIP[3'](16:0/16:0)
  • PI(3)P (16:0/16:0)
Molecular Formula
C41H78O16P2 • 2NH4
Formula Weight
925.1
Purity
≥98%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
CHCl3:CH3OH:H2O (3:2:0.5): >1 mg/mlH2O: <1 mg/ml
SMILES
CCCCCCCCCCCCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H](O)[C@H]1O)([O-])=O)OC(CCCCCCCCCCCCCCC)=O)=O.[NH4+].[NH4+]
InChi Code
InChI=1S/C41H80O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)53-31-33(55-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-54-59(51,52)57-41-38(46)36(44)37(45)40(39(41)47)56-58(48,49)50;;/h33,36-41,44-47H,3-32H2,1-2H3,(H,51,52)(H2,48,49,5
InChi Key
XAERIJXJLCXLHF-GVWNKXCRSA-N
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 µg

    $70

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    500 µg

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    1 mg

    $535

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    Product Description

    PtdIns-(3)-P1 can be further phosphorylated to give triphosphates such as PtdIns-(3,4,5)-P3. These can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates (IP3). The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references 1,2,3.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Majerus, P.W. Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250 (1992).

    2. Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. The Journal of Biological Chemisty 271(43), 26453-26456 (1996).

    3. Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361(6410), 315-325 (1993).