A synthetic analog of natural PtdIns
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PtdIns-(3,4)-P2 (1,2-dipalmitoyl) (sodium salt)

Item No. 64922

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(1,2R-dihexadecanoylphosphatidyl)inositol-3,4-bisphosphate, trisodium salt
Synonyms
  • DPPI-3,4-P2
  • Phosphatidylinositol-3,4-diphosphate C-16
  • PI(3,4)P2 (16:0/16:0)
  • PIP2[3',4'](16:0/16:0)
Molecular Formula
C41H78O19P3 • 3Na
Formula Weight
1036.9
Purity
≥98%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
50 mM HEPES*: 5 mg/mlCHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): 1 mg/ml (opaque solution)
SMILES
CCCCCCCCCCCCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](O)[C@H]1O)([O-])=O)OC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C41H81O19P3.3Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-39-36(44)37(45)40(58-61(47,48)49)41(38(39)46)59-62(50,51)52;;;/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54
InChi Key
STJBVCQNLFXTFJ-AAOIFZENSA-K
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 µg

    $55

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    500 µg

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    Product Description

    The phosphatidylinositols (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292(5821), 367-369 (1981).

    2. Majerus, P.W. Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250 (1992).