A convenient, fluorescence-based method for screening HDAC8 inhibitors
Features
  • Screen for inhibitors of HDAC8
  • Assay 45 samples in duplicate
  • Includes trichostatin A as a positive control
  • Plate-based fluorometric measurement (ex 360 nm, em 460 nm)
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HDAC8 Inhibitor Screening Assay Kit

Item No. 700230

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Histone Deacetylase 8 Inhibitor Screening Assay Kit
Emission
460 nm
Excitation
360 nm
License
Sold under license from Cyclex.
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 wells

    $383

    Add
    Cayman Chemical
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    Product Description

    Cayman’s HDAC8 Inhibitor Screening Assay provides a convenient fluorometric method for screening HDAC8 inhibitors in a two-step reaction. In the first step, the substrate, which is comprised of the p53 sequence Arg-His-Lys-Lys(ε-acetyl)-AMC, is incubated with recombinant human HDAC8. Deacetylation sensitizes the substrate such that treatment with the developer in the second step releases a fluorescent product. The fluorophore can be easily analyzed using an excitation wavelength of 360 nm and an emission wavelength of 460 nm.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.