A convenient method for screening human PAD1 inhibitors
Features
  • Screen for inhibitor of PAD1
  • Assay 45 samples in duplicate
  • Plate-based fluorometric measurement (ex: 405-415 nm; em: 470-480 nm)
  • Orthogonal assay to Cayman's PAD1 Inhibitor Screening Assay Kit (AMC) (Item No. 701440)
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PAD1 Inhibitor Screening Assay Kit (Ammonia)

Item No. 701450

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • PADI1
  • PDI1
  • Peptidylarginine Deiminase 1
  • Protein Arginine Deiminase 1
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 wells

    $543

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    Product Description

    Cayman’s PAD1 Inhibitor Screening Assay Kit (Ammonia) provides a convenient method for screening human PAD1 inhibitors. PAD1 deiminates N-α-benzoyl-L-arginine ethyl ester (BAEE), a non-natural substrate with similar kinetic properties to the natural substrates, producing ammonia.1 Ammonia reacts with a detector resulting in a fluorescent product. Fluorescence is then analyzed with an excitation wavelength of 405-415 nm and an emission wavelength of 470-480 nm.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kearney, P.L., Bhatia, M., Jones, N.G., et al. Kinetic characterization of protein arginine deiminase 4: A transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry 44(31), 10570-10582 (2005).