A convenient fluorometric method of screening human FSP1 inhibitors
Features
  • Screen for inhibitors of FSP1
  • Includes recombinant human FSP1 and positive control FSP1 inhibitor iFSP1
  • Assay 29 samples in triplicate in 96-well assay or assay 125 samples in triplicate in 384-well assay
  • Plate-based fluorometric measurement (Ex/Em = 540/590 nm)
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FSP1 Fluorescent Inhibitor Screening Assay Kit

Item No. 701900

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    384 wells

    $759

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    96 wells

    $759

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    Cayman Chemical
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    Product Description

    Cayman's FSP1 Fluorescent Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human FSP1, a negative regulator of the ferroptosis pathway. The assay measures the reduction of resazurin by FSP1 into resorufin, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 540 and 590 nm, respectively. The potent and reversible FSP1 inhibitor iFSP1 is included as a positive control and inhibits FSP1 with an IC50 value of 267 ± 47 nM.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.