For the loading of preformulated, cargo-ready, empty, lyophilized LNPs
Features
  • Prepare lipid nanoparticles without specialized equipment
  • Load and transfect with RNA cargo of choice
  • Deliver RNA to hard-to-transfect cell lines and primary cell cultures
  • Preserve cell viability, gentle on cells
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LipidLaunch™ SM-102 LNP Kit (Loadable)

Item No. 702620

Technical Information
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Cayman Chemical
    Product Description

    Cayman’s LipidLaunch™ SM-102 LNP Kit (Loadable) provides cargo-ready, empty, lyophilized SM-102 LNPs. Following resuspension, these LNPs are capable of rapid encapsulation of nucleic acids, without the need for incubation steps, enabling subsequent delivery to target cells or other downstream research applications. LipidLaunch™ LNPs (Loadable) demonstrate very low toxicity compared to traditional lipid-based transfection methods.

    Conventionally loaded LNPs typically require specialized equipment to ensure consistent control of particle size, while also requiring large reaction volumes. LipidLaunch™ SM-102 LNPs (Loadable) enable users to encapsulate cargo in low reaction volumes offering greater flexibility in the scale of preparation while preserving costly nucleic acid cargo.

    LipidLaunch™ SM-102 LNP (Loadable) performance is dependent on a variety of factors, including cargo type and cell line, so optimization of these parameters is necessary. To aid in optimization, consider using Cayman’s LipidLaunch™ LNP Screening Set (Loadable) (Item No. 502868) or LipidLaunch™ SM-102 LNPs preloaded with luciferase, mCherry, or GFP mRNA (Item Nos. 39318 | 39319 | 39320).

    For more information, please see Cayman's application note: Encapsulation and Transfection of RNA Using LipidLaunch™ SM-102 Lipid Nanoparticles (Loadable)

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Frey, A., Clulo, K., Fei, Y., et alTargeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma. Cell Rep. 44(10), 116359 (2025).