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Cayman’s LipidLaunch™ SM-102 LNP Kit (Loadable) provides cargo-ready, empty, lyophilized SM-102 LNPs. Following resuspension, these LNPs are capable of rapid encapsulation of nucleic acids, without the need for incubation steps, enabling subsequent delivery to target cells or other downstream research applications. LipidLaunch™ LNPs (Loadable) demonstrate very low toxicity compared to traditional lipid-based transfection methods.
Conventionally loaded LNPs typically require specialized equipment to ensure consistent control of particle size, while also requiring large reaction volumes. LipidLaunch™ SM-102 LNPs (Loadable) enable users to encapsulate cargo in low reaction volumes offering greater flexibility in the scale of preparation while preserving costly nucleic acid cargo.
LipidLaunch™ SM-102 LNP (Loadable) performance is dependent on a variety of factors, including cargo type and cell line, so optimization of these parameters is necessary. To aid in optimization, consider using Cayman’s LipidLaunch™ LNP Screening Set (Loadable) (Item No. 502868) or LipidLaunch™ SM-102 LNPs preloaded with luciferase, mCherry, or GFP mRNA (Item Nos. 39318 | 39319 | 39320).
For more information, please see Cayman's application note: Encapsulation and Transfection of RNA Using LipidLaunch™ SM-102 Lipid Nanoparticles (Loadable)
WARNING This product is not for human or veterinary use.
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