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Cayman’s LipidLaunch™ C14-4 LNP Kit (Loadable) provides cargo-ready, empty C14-4 LNPs. These LNPs are capable of rapid encapsulation of nucleic acids, without the need for incubation steps, enabling subsequent delivery to target cells or other downstream research applications. LipidLaunch™ LNPs (Loadable) demonstrate very low toxicity compared to traditional lipid-based transfection methods.
Conventionally loaded LNPs typically require specialized equipment to ensure consistent control of particle size, while also requiring large reaction volumes. LipidLaunch™ C14-4 LNPs (Loadable) enable users to encapsulate cargo in low reaction volumes offering greater flexibility in the scale of preparation while preserving costly nucleic acid cargo. The reagent has been optimized for transfection of primary and cultured T cells with mRNA.
LipidLaunch™ C14-4 LNP (Loadable) performance is dependent on a variety of factors, including cargo type and cell line, so optimization of these parameters is necessary. To aid in optimization, consider using Cayman’s LipidLaunch™ LNP Screening Set (Loadable) (Item No. 502868).
WARNING This product is not for human or veterinary use.