A potent inhibitor of NF-κB activation
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Caffeic Acid phenylethyl ester

Item No. 70750

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(E)-3-(3,4-dihydroxyphenyl)-2-propenoic acid, 2-phenylethyl ester
CAS Number
104594-70-9
Synonyms
  • CAPE
  • 2-Phenylethyl Caffeate
  • β-Phenylethyl Caffeate
Molecular Formula
C17H16O4
Formula Weight
284.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 30 mg/ml
λmax
246, 300, 331 nm
SMILES
OC1=C(O)C=C(/C=C/C(OCCC2=CC=CC=C2)=O)C=C1
InChi Code
InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
InChi Key
SWUARLUWKZWEBQ-VQHVLOKHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $69

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    100 mg

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    500 mg

    $363

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    1 g

    $461

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    Cayman Chemical
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    Product Description

    Caffeic acid phenylethyl ester is an active component of propolis from honeybee hives. It is known to have antimitogenic, anticarcinogenic, anti-inflammatory, and immunomodulatory properties. It is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Natarajan, K., Singh, S., Burke, T.R., Jr., et al. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc. Natl. Acad. Sci. USA 93, 9090-9095 (1996).