Pricing updated 2019-02-20. Prices are subject to change without notice.
A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health.1,2,3 Antioxidant triterpenes are less common. Celastrol is a triterpenoid antioxidant compound isolated from Chinese thunder god vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-
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Frémont, L., Belguendouz, L., and Delpal, S. Antioxidant activity of resveratrol and alcohol-
2. Johnson, J.L., and Maddipati, K.R. Paradoxical effects of resveratrol on the two prostaglandin H synthases Prostaglandins & Other Lipid Mediators 56, 131-143 (1998).
Miller, N.J., and Rice-
4. Sassa, H., Takaishi, Y., and Terada, H. The triterpene celastrol as a very potent inhibitor of lipid peroxidation in mitochondria Biochemical and Biophysical Research Communications 172(2), 890-897 (1990).