A substrate used to quantitate peroxidase activity
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PPHP

Item No. 75750

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-phenyl-4E-pentenyl-1-hydroperoxide
CAS Number
87864-20-8
Molecular Formula
C11H14O2
Formula Weight
178.2
Purity
≥98%
Formulation (Request formulation change)
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: >10 mg/mlDMSO: >7 mg/mlEthanol: >10 mg/mlPBS pH 7.2: >540 µg/ml
λmax
250 nm
SMILES
OOCCC/C=C/c1ccccc1
InChi Code
InChI=1S/C11H14O2/c12-13-10-6-2-5-9-11-7-3-1-4-8-11/h1,3-5,7-9,12H,2,6,10H2/b9-5+
InChi Key
MQSMIOKTOYAPHO-WEVVVXLNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $109

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    1 mg

    $207

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    5 mg

    $763

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    10 mg

    $1,089

    Add
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    Product Description

    PPHP is a substrate for the measurement of peroxidase enzymes. PPHP has been used to quantitate the peroxidase activity of COX-1 and COX-2.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Weller, P.E., Markey, C.M., and Marnett, L.J. Enzymatic reduction of 5-phenyl-4-pentenyl-hydroperoxide: Detection of peroxidases and identification of peroxidase reducing substrates. Arch. Biochem. Biophys. 243(2), 633-643 (1985).

    2. Odenwaller, R., Maddipati, K.R., and Marnett, L.J. Detection of a higher oxidation state of manganese-prostaglandin endoperoxide synthase. The Journal of Biological Chemisty 267, 13863-13869 (1992).

    3. Samokyszyn, V.M., Freeman, J.P., Maddipati, K.R., et al. Peroxidase-catalyzed oxidation of pentachlorophenol. Chem. Res. Toxicol. 8, 349-355 (1995).