A peroxynitrite decomposition catalyst
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FeTMPyP

Item No. 75854

Technical Information
Formal Name
[[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[1-methylpyridiniumato]](2-)]-Iron(5+), pentachloride
CAS Number
133314-07-5
Molecular Formula
C44H36FeN8 • 5Cl
Formula Weight
Purity
≥98%
A crystalline solid
0.1 M Tris -HCl, 1 mM EDTA, pH 9.0: 10 mg/mlPBS pH 7.2: 10 mg/ml
λmax
423 nm
SMILES
C[N+]1=CC=C(C=C1)C2=C3[N-]4[Fe+3]5([N]6=C2C=CC6=C7C(C=C8)=CC=[N+]8C)[N-]9C7=CC=C9C(C(C=C%10)=CC=[N+]%10C)=C(C=C%11)[N]5=C%11C(C(C=C%12)=CC=[N+]%12C)=C4C=C3.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-]
InChi Code
InChI=1S/C44H36N8.5ClH.Fe/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;;;;;;/h5-28H,1-4H3;5*1H;/q+2;;;;;;+3/p-5
InChi Key
YFVSQZUYMGLAPN-UHFFFAOYSA-I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.2 x 106 M−1s−1 with a turnover number of 360 ± 170 s−1.1 The predominant product (>90%) of this reaction is nitrate, with a minor amount of nitrite also formed (~6%), at pH 7.4.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stern, M.K., Jensen, M.P., and Kramer, K. Peroxynitrite decomposition catalysts. J. Am. Chem. Soc. 118(36), 8735-8736 (1996).