A non-selective inhibitor of all NOS isoforms
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S-(2-aminoethyl) Isothiourea (dihydrobromide)

Item No. 81005

Technical Information
Formal Name
2-aminoethyl carbamimidothioate, dihydrobromide
CAS Number
56-10-0
Synonyms
  • Antiradon
  • NSC 22877
Molecular Formula
C3H9N3S • 2HBr
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
Water: Soluble
SMILES
N/C(SCCN)=N/[H].Br.Br
InChi Code
InChI=1S/C3H9N3S.2BrH/c4-1-2-7-3(5)6;;/h1-2,4H2,(H3,5,6);2*1H
InChi Key
XDVMCVGTDUKDHL-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    S-(2-aminoethyl) Isothiourea is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the Ki values are 1.8, 2.1, and 0.59 µM, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Garvey, E.P., Oplinger, J.A., Tanoury, G.J., et alPotent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. The Journal of Biological Chemisty 269(43), 26669-26676 (1994).