A nitric oxide scavenger
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Carboxy-PTIO (potassium salt)

Item No. 81540

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-1H-imidazolyl-1-oxy-3-oxide, monopotassium salt
CAS Number
148819-94-7
Molecular Formula
C14H16N2O4 • K
Formula Weight
315.4
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3.3 mg/mlDMSO: 1.4 mg/mlEthanol: 1.6 mg/mlPBS (7.2): 35 mg/ml
λmax
232, 282, 368 nm
SMILES
[O-][N+]1=C(C2=CC=C(C([O-])=O)C=C2)N([O-])C(C)(C)C1(C)C.[K+]
InChi Code
InChI=1S/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q-1;+1/p-1
InChi Key
CUYIQXAMAUOMKG-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $41

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    10 mg

    $70

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    50 mg

    $245

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    100 mg

    $448

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    Product Description

    Carboxy-PTIO is a NO scavenger. It reacts stoichiometrically with NO and can be used for EPR detection of NO.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Akaike, T., Yoshida, M., Miyamoto, Y., et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/∙NO through a radical reaction. Biochemistry 32, 827-832 (1993).

    2. Pfeiffer, S., Leopold, E., Hemmens, B., et al. Interference of carboxy-PTIO with nitric oxide-and peroxynitrite-mediated reactions. Free Radic. Biol. Med. 22, 787-794 (1997).