A precursor in the synthesis of BH4
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Product Type

Small Molecule Modulators
Small Molecule Inhibitors

Research Area

Cell Biology

7,8-dihydro-L-Biopterin

Item No. 81882

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-6-(1R,2S-dihydroxypropyl)-7,8-dihydro-4(1H)-pteridinone
CAS Number
6779-87-9
Synonyms
  • BH2
  • Dihydrobiopterin
Molecular Formula
C9H13N5O3
Formula Weight
239.2
Purity
≥97%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Water: Sparingly soluble
λmax
234, 279, 332 nm
SMILES
NC(N([H])C1=C2N=C([C@@H](O)[C@@H](O)C)CN1[H])=NC2=O
InChi Code
InChI=1S/C9H13N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,6,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,6-/m0/s1
InChi Key
FEMXZDUTFRTWPE-DZSWIPIPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

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    50 mg

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    Product Description

    BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shen, R., Alam, A., and Zhang, Y. Inhibition of GTP cyclohydrolase I by pterins. Biochim. Biophys. Acta 965(1), 9-15 (1988).