A nitric oxide donor
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DPTA NONOate

Item No. 82110

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(Z)-1-[N-(3-aminopropyl)-N-(3-ammoniopropyl)amino]diazen-1-ium-1,2-diolate
CAS Number
146724-95-0
Synonyms
  • Dipropylenetriamine NONOate
Molecular Formula
C6H17N5O2
Formula Weight
191.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
λmax
252 nm
SMILES
[NH3+]CCCN(N(N=O)[O-])CCCN
InChi Code
InChI=1S/C6H16N5O2/c7-3-1-5-10(6-2-4-8)11(13)9-12/h1-8H2/q-1/p+1
InChi Key
MSKMSUCXUZVDBD-UHFFFAOYSA-O
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    10 mg

    $50

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    25 mg

    $106

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    50 mg

    $186

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    100 mg

    $372

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    Product Description

    DPTA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. The Journal of Organic Chemistry 58(6), 1472-1476 (1993).

    2. Keefer, L.K., Nims, R.W., Davies, K.M., et al. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol. 268, 281-293 (1996).