A nitric oxide donor
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MAHMA NONOate

Item No. 82130

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate
CAS Number
146724-86-9
Synonyms
  • Methylamine hexamethylene methylamine NONOate
Molecular Formula
C8H20N4O2
Formula Weight
204.3
Formulation (Request formulation change)
A crystalline solid
λmax
250 nm
SMILES
C[N+]([H])([H])CCCCCCN(N(N=O)[O-])C
InChi Code
InChI=1S/C8H19N4O2/c1-9-7-5-3-4-6-8-11(2)12(14)10-13/h9H,3-8H2,1-2H3/q-1/p+1
InChi Key
WASRCWNCCFPNEJ-UHFFFAOYSA-O
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $42

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    25 mg

    $90

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    50 mg

    $137

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    100 mg

    $251

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    Product Description

    MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. The Journal of Organic Chemistry 58(6), 1472-1476 (1993).

    2. Keefer, L.K., Nims, R.W., Davies, K.M., et al. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol. 268, 281-293 (1996).

    Product Citations

    Li, T., Wang, L., Lin, S., et al. Rational Design and Bioimaging Applications of Highly Specific "Turn-On" Fluorescent Probe for Hypochlorite. Bioconjug. Chem. 29(8), 2838-2845 (2018).