An NO-releasing prodrug
Related Products
Active Metabolite(s)
82220SIN-1 (chloride)
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Molsidomine

Item No. 82200

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(ethoxycarbonyl)-3-(4-morpholinyl)-sydnone imine
CAS Number
25717-80-0
Synonyms
  • Corvaton
  • Morsydomine
Molecular Formula
C9H14N4O4
Formula Weight
242.2
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetone: sparingly solubleBenzene: sparingly solubleCHCl3: >40 mg/mlCHCl3: freely solubledil HCl: solubleDMF: >13 mg/mlDMSO: >70 mg/mlEthanol: >35 mg/mlEther: sparingly solubleEthyl acetate: solubleH2O: sparingly solubleMethanol: solublePBS pH 6.5: >12 mg/mlPBS pH 7.2: > 9 mg/ml
λmax
230, 319 nm
SMILES
O=C(OCC)[N-]C1=C[N+](N2CCOCC2)=NO1
InChi Code
InChI=1S/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3
InChi Key
XLFWDASMENKTKL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $16

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    500 mg

    $59

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    1 g

    $98

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    5 g

    $423

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    Product Description

    Molsidomine is a NO-releasing prodrug. Liver esterases convert molsidomine to the active metabolite, SIN-1 (half-life in plasma is 1-2 hours), which then releases NO.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nitz, R.E., and Fiedler, V. Molsidomine: Alternative approaches to treat myocardial ischemia. Pharmacotherapy 7, 28-37 (1987).

    2. Rosenkranz, B., Winkelmann, B.R., and Parnham, M.J. Clinical pharmacokinetics of molsidomine. Clin. Pharmacokinet. 30(5), 372-384 (1996).