A synthetic glucocorticoid
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Fluorometholone

Item No. 9000157

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-fluoro-11β,17-dihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione
CAS Number
426-13-1
Synonyms
  • NSC 33001
  • U-8614
Molecular Formula
C22H29FO4
Formula Weight
376.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly SolubleMethanol: Slightly Soluble
SMILES
O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(C)=O)=C1
InChi Code
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChi Key
FAOZLTXFLGPHNG-KNAQIMQKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

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    250 mg

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    500 mg

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    Product Description

    Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay).1,2 Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment.3 Formulations containing fluorometholone have been used for the treatment of eye inflammation.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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