An FP receptor agonist, a derivative of PGF, and a prodrug form of AR-102
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AR-102

Item No. 9000362

Product Insert (PDF)
Technical Information
Formal Name
(1R,2R,3R,5S)-2-[(3R)-3-benzo[b]thien-2-yl-3-hydroxypropyl]-3,5-dihydroxy-cyclopentaneheptanoic acid, 3-hydroxy-2,2-bis(hydroxymethyl)propyl ester
CAS Number
955005-63-7
Synonyms
  • Dukeprost pentaerthrityl ester
Molecular Formula
C28H42O8S
Formula Weight
538.7
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
O[C@@H]1[C@H](CCCCCCC(OCC(CO)(CO)CO)=O)[C@@H](CC[C@@H](O)C2=CC3=CC=CC=C3S2)[C@H](O)C1
InChi Code
InChI=1S/C28H42O8S/c29-15-28(16-30,17-31)18-36-27(35)10-4-2-1-3-8-20-21(24(34)14-23(20)33)11-12-22(32)26-13-19-7-5-6-9-25(19)37-26/h5-7,9,13,20-24,29-34H,1-4,8,10-12,14-18H2/t20-,21-,22-,23+,24-/m1/s1
InChi Key
UCGXLCPNFJKWEF-ZSXJVMONSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $83

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    5 mg

    $330

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    10 mg

    $578

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    25 mg

    $929

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    Product Description

    AR-102 is an FP receptor agonist, a derivative of prostaglandin F (PGF), and a prodrug form of AR-102 (free acid) (Item Nos. 10008049 | 43439).1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fogagnolo, P., and Rossetti, L. Medical treatment of glaucoma: Present and future. Expert Opin. Investig. Drugs 20(7), 947-959 (2011).

    2. Wierzbowska, J., Robaszkiewicz, J., Figurska, M., et al. Future possibilities in glaucoma therapy. Med. Sci. Monit. 16(11), RA252-RA259 (2010).