An internal standard for the quantification of cholesteryl palmitate
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Cholesteryl-d7 Palmitate

Item No. 9000422

Technical Information
Formal Name
(3β)-cholest-5-en-25,26,26,26,27,27,27-d7-3-ol, 3-hexadecanoate
CAS Number
1416275-32-5
Synonyms
  • 16:0 Cholesterol-d7 ester
  • Cholesterol-d7 Palmitate
  • 16:0(CE-d7)
  • CE-d7(16:0)
Molecular Formula
C43H69D7O2
Formula Weight
Purity
≥99% deuterated forms (d1-d7)
Formulation
A 10 mg/ml solution in chloroform
Chloroform: Sparingly soluble: 1-10 mg/ml
SMILES
C[C@]12C(C[C@@H](OC(CCCCCCCCCCCCCCC)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@@H](CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C)[H]
InChi Code
InChI=1S/C43H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-23-41(44)45-36-28-30-42(5)35(32-36)24-25-37-39-27-26-38(34(4)22-20-21-33(2)3)43(39,6)31-29-40(37)42/h24,33-34,36-40H,7-23,25-32H2,1-6H3/t34-,36+,37+,38-,39+,40+,42+,43-/m1/s1/i2D3,3D3,33D
InChi Key
BBJQPKLGPMQWBU-WZRYUIABSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cholesteryl-d7 palmitate is an internal standard for the quantification of cholesteryl palmitate (Item No. 26473) by GC- or LC-MS. Cholesteryl palmitate is a cholesterol ester. It is a major cholesterol ester found in human meibum and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eyes.1 Cholesteryl palmitate levels in amniotic fluid are decreased in pregnancies in which infants later developed respiratory distress syndrome and in patients with well-controlled diabetes.2,3 Levels of cholesteryl palmitate are increased in bronchoalveolar lavage fluid (BALF) from patients with chronic interstitial pneumonia.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shine, W.E., and McCulley, J.P. Polar lipids in human meibomian gland secretions. Curr. Eye Res. 26(2), 89-94 (2003).

    2. Ludmir, J., Alvarez, J.G., Mennuti, M.T., et alCholesteryl palmitate as a predictor of fetal lung maturity. Am. J. Obstet. Gynecol. 157(1), 84-88 (1987).

    3. Ludmir, J., Alvarez, J.G., Landon, M.B., et alAmniotic fluid cholesteryl palmitate in pregnancies complicated by diabetes mellitus. Obstet. Gynecol. 73(3 Pt.1), 360-362 (1988).

    4. Fukuhara, N., Tachihara, M., Tanino, Y., et alCholesteryl palmitate crystals in bronchoalveolar lavage fluid smears as a possible prognostic biomarker for chronic interstitial pneumonia: A preliminary study. Respir. Investig. 54(2), 109-115 (2016).