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JWH 203

Item No. 9000736

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone
CAS Number
864445-54-5
Molecular Formula
C21H22ClNO
Formula Weight
339.9
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 5 mg/ml
λmax
212, 246, 304 nm
SMILES
CCCCCN1C=C(C(CC2=C(Cl)C=CC=C2)=O)C3=CC=CC=C31
InChi Code
InChI=1S/C21H22ClNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3
InChi Key
YDINKDBAZJOSLV-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $77

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    10 mg

    $145

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    25 mg

    $339

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    Product Description

    JWH 203 is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid (CB) agonist with Ki values of 8.0 and 7.0 nM at the CB1 and CB2 receptors, respectively.1 Similar to the related 2'-methoxy compound JWH 250, JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole CB compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 receptors (JWH 250 Kis = 11 and 33 nM, respectively).1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg. Med. Chem. Lett. 15(18), 4110-4113 (2005).

    Product Citations

    Ciolino, L.A. Quantitation of synthetic cannabinoids in plant materials using high performance liquid chromatography with UV detection (validated method). J. Forensic Sci. 60(5), 1171-1181 (2015).