Fluorescently tagged ceramide
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C10 AV Ceramide (d18:1/10:0)

Item No. 9000753

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(11E)-12-(9-anthracenyl)-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-11-dodecenamide
CAS Number
1263052-40-9
Synonyms
  • Anthrylvinyl Ceramide
  • AV Ceramide
  • AV Ceramide (d18:1/10:0)
  • AV Cer(d18:1/10:0)
Molecular Formula
C44H65NO3
Formula Weight
656.0
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 25 mg/ml
λmax
256 nm
SMILES
OC[C@@H]([C@@](O)([H])/C=C/CCCCCCCCCCCCC)C(CCCCCCCCC/C=C\C1=C(C=CC=C2)C2=CC3=C1C=CC=C3)=O
InChi Code
InChI=1S/C44H65NO3/c1-2-3-4-5-6-7-8-9-10-13-16-19-22-33-43(47)42(36-46)45-44(48)34-23-20-17-14-11-12-15-18-21-32-41-39-30-26-24-28-37(39)35-38-29-25-27-31-40(38)41/h21-22,24-33,35,42-43,46-47H,2-20,23,34,36H2,1H3,(H,45,48)/b32-21+,33-22+/t42-,43+/m0/
InChi Key
HMEXREVDGZSXDA-YYOCMJKUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $108

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    5 mg

    $481

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    10 mg

    $856

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    25 mg

    $1,868

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    Product Description

    AV-Ceramide is a fluorescently tagged probe consisting of C-10 ceramide with an anthrylvinyl (AV) group attached to the end of the acyl chain. The AV group, being relatively small and non-polar, readily orients within the central region of a lipid bilayer.1 The transfer or transport of lipids labeled with AV is commonly evaluated in real time using fluorescence resonance energy transfer, with a second fluorophore.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Polozov, I.V., Molotkovsky, J.G., and Bergelson, L.D. Anthrylvinyl-labeled phospholipids as membrane probes: The phosphatidylcholine-phosphatidylethanolamine system. Chem. Phys. Lipids 69(3), 209-218 (1994).

    2. Mattijus, P., Molotkovsky, J.G., Smaby, J.M., et al. A fluorescence resonance energy transfer approach for monitoring protein-mediated glycolipid transfer between vesicle membranes. Anal. Biochem. 268(2), 297-304 (1999).

    3. Tuuf, J., Kjellberg, M.A., Molotkovsky, J.G., et al. The intermediate ceramide transport catalyzed by CERT is sensitive to the lipid environment. Biochim. Biophys. Acta 1808, 229-235 (2011).