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Parent Compound(s)
13633JWH 019 15664JWH 019 (exempt preparation)
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JWH 019 5-hydroxyindole metabolite

Item No. 9000764

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • JWH 019-M2
Technical Information
Formal Name
(1-hexyl-5-hydroxy-1H-indol-3-yl)-1-naphthalenyl-methanone
CAS Number
1379604-70-2
Molecular Formula
C25H25NO2
Formula Weight
371.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 15 mg/mlEthanol: 0.15 mg/ml
λmax
219, 256, 281,323 nm
SMILES
O=C(C1=CN(CCCCCC)C2=C1C=C(O)C=C2)C3=CC=CC4=C3C=CC=C4
InChi Code
InChI=1S/C25H25NO2/c1-2-3-4-7-15-26-17-23(22-16-19(27)13-14-24(22)26)25(28)21-12-8-10-18-9-5-6-11-20(18)21/h5-6,8-14,16-17,27H,2-4,7,15H2,1H3
InChi Key
VEOUPNIXKBJMFF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB) and the peripheral CB receptors.1 It has been detected in certain herbal blends sold for human consumption. JWH 019 5-hydroxyindole metabolite is expected to be a major metabolite of JWH 019, detectable in serum and urine.2,3 The biological effects of the metabolite are not known. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).

    2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci. Int. 200(1-3), 141-147 (2010).

    3. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS. Anal. Bioanal. Chem. 386(5), 1345-1355 (2006).

    Product Citations

    Hutter, M., Broecker, S., Kneisel, S., et al. Metabolism of synthetic cannabinoid receptor agonists encountered in clinical casework: Major in vivo phase I metabolites of JWH-007, JWH-019, JWH-203, JWH-307, UR-144, XLR-11, AM-2201, MAM-2201 and AM-694 inhuman urine using LC-MS/MS. Curr. Pharm. Biotechnol. 19(2), 144-162 (2018).