An Analytical Reference Standard
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Parent Compound(s)
10644JWH 210
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JWH 210 5-hydroxyindole metabolite

Item No. 9000771

Technical Information
Formal Name
(4-ethyl-1-naphthalenyl)(5-hydroxy-1-pentyl-1H-indol-3-yl)-methanone
CAS Number
1427325-81-2
Molecular Formula
C26H27NO2
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 20 mg/mlDMSO: 20 mg/ml
λmax
221, 256, 282, 323 nm
SMILES
O=C(C1=CN(CCCCC)C2=C1C=C(O)C=C2)C3=C4C(C=CC=C4)=C(CC)C=C3
InChi Code
InChI=1S/C26H27NO2/c1-3-5-8-15-27-17-24(23-16-19(28)12-14-25(23)27)26(29)22-13-11-18(4-2)20-9-6-7-10-21(20)22/h6-7,9-14,16-17,28H,3-5,8,15H2,1-2H3
InChi Key
HNBLEUDMHIXXJB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with 5-hydroxyindole metabolites detected both in liver secretions and in urine.1,2,3 JWH 210 5-hydroxyindole metabolite is an expected metabolite of JWH 210, detectable both in serum and urine. Its biological activities have yet to be determined. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Teske, J., Weller, J.P., Fieguth, A., et alSensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27), 2659-2663 (2010).

    2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci. Int. 200(1-3), 141-147 (2010).

    3. Wintermeyer, A., Möller, I., Thevis, M., et alIn vitro phase I metabolism of the synthetic cannabimimetic JWH-018. Anal. Bioanal. Chem. 398(5), 2141-2153 (2010).