CYP450 metabolite of palmitic acid
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16-hydroxy Hexadecanoic Acid

Item No. 9000789

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
16-hydroxy-hexadecanoic acid
CAS Number
506-13-8
Synonyms
  • FA 16:0;O
  • 16-hydroxy Palmitic Acid
  • Juniperic Acid
Molecular Formula
C16H32O3
Formula Weight
272.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS(pH 7.2) (1:2): 0.33 mg/mlEthanol: 2.5 mg/ml
SMILES
C(CCCCCCCC(=O)O)CCCCCCCO
InChi Code
InChI=1S/C16H32O3/c17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(18)19/h17H,1-15H2,(H,18,19)
InChi Key
UGAGPNKCDRTDHP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Product Description

    16-hydroxy Hexadecanoic acid is a metabolite of the saturated fatty acid palmitic acid (16:0) that has been hydroxylated on its terminal (ω) carbon. It is produced by ω-hydroxylation of palmitic acid by cytochrome P450 in both plants and animals.1,2,3,4 In plants, it is commonly a component of cutin.5,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Benveniste, I., Saito, T., Wang, Y., et al. Evolutionary relationship and substrate specificity of Arabidopsis thaliana fatty acid ω-hydroxylase. Plant Sci. 170(2), 326-328 (2006).

    2. Li, H., Pinot, F., Sauveplane, V., et al. Cytochrome P450 family member CYP704B2 catalyzes the ω-hydroxylation of fatty acids and is require for anther cutin biosynthesis and pollen exine formation in rice. Plant Cell 22(1), 173-190 (2010).

    3. Roman, L.J., Palmer, C.N.A., Clark, J.E., et al. Expression of rabbit cytochromes P4504A which catalyze the ω-hydroxylation of arachidonic acid, fatty acid, and prostaglandins. Arch. Biochem. Biophys. 307(1), 57-65 (1993).

    4. Aoyama, T., Hardwick, J.P., Imaoka, S., et al. Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the ω- and (ω-1)-hydroxylation of fatty acids and the (ω-1)-hydroxylation of prostaglandins E1 and F2α. J. Lipid Res. 31(8), 1477-1482 (1990).

    5. Peshel, S., Franke, R., Schreiber, L., et al. Composition of the cuticle of developing sweet cherry fruit. Phytochemistry 68(7), 1017-1025 (2007).