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JWH 018 2'-naphthyl-N-(2,2-dimethylpropyl) isomer

Item № 9001008
CAS № 1869954-38-0
Purity ≥98%
product image
                (CAS 1869954-38-0)

Formulation:  A crystalline solid

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $49.00 0.00
     5 mg $221.00 0.00
     10 mg $392.00 0.00

Pricing updated 2019-03-26. Prices are subject to change without notice.

Description

JWH 018 (1-pentyl-3-(1-naphthoyl)indole) is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively).1 This cannabimimetic compound has frequently been found in herbal blends. 2,3,4 JWH 018 2’-naphthyl-N-(2,2-dimethylpropyl) isomer differs structurally from JWH 018 by having the naphthyl group attached at the 2’ position and 2,2-dimethylpropyl in place of the pentyl chain. The biological activities of this compound have not been characterized.

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Technical Information
Formal Name
[1-(2,2-dimethylpropyl)-1H-indol-3-yl]-2-naphthalenyl-methanone
CAS Number
1869954-38-0
Molecular Formula
C24H23NO
Formula Weight
341.5
Purity
≥98%
Formulation
A crystalline solid
λmax
216, 252, 325 nm
SMILES
CC(C)(C)CN1C2=CC=CC=C2C(C(C3=CC=C(C=CC=C4)C4=C3)=O)=C1
InChI Code
InChI=1S/C24H23NO/c1-24(2,3)16-25-15-21(20-10-6-7-11-22(20)25)23(26)19-13-12-17-8-4-5-9-18(17)14-19/h4-15H,16H2,1-3H3
InChI Key
VAWLMOLQJCGJAZ-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2), 133-140 (2000).

2. Auwärter, V., Dresen, S., Weinmann, W., et al. “Spice” and other herbal blends: Harmless incense or cannabinoid designer drugs? Journal of Mass Spectrometry 44, 832-837 (2009).

3. Lindigkeit, R., Boehme, A., Eiserloh, I., et al. Spice: A never ending story? Forensic Science International 191, 58-63 (2009).

4. Uchiyama, N., Kikura-Hanajiri, R., Kawahara, N., et al. Identification of a cannabimimetic indole as a designer drug in a herbal product Forensic Toxicol. 27, 61-66 (2009).

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