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JWH 018 2'-naphthyl-N-(1-methylbutyl) isomer

Item № 9001009
Purity ≥98%
product image

Formulation:  A solution in methanol

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $49.00 0.00
     5 mg $221.00 0.00
     10 mg $392.00 0.00

Pricing updated 2019-03-26. Prices are subject to change without notice.

Description

JWH 018 (1-pentyl-3-(1-naphthoyl)indole) is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively).1 This cannabimimetic compound has frequently been found in herbal blends. 2,3,4 JWH 018 2’-naphthyl-N-(1-methylbutyl) isomer differs structurally from JWH 018 by having the naphthyl group attached at the 2’ position and 1-methylbutyl in place of the pentyl chain. The biological activities of this compound have not been characterized.

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Technical Information
Formal Name
naphthalen-2-yl(1-(pentan-2-yl)-1H-indol-3-yl)methanone
Molecular Formula
C24H23NO
Formula Weight
341.5
Purity
≥98%
Formulation
A solution in methanol
λmax
216, 252, 326 nm
SMILES
O=C(C1=CC=C(C=CC=C2)C2=C1)C3=CN(C(C)CCC)C4=CC=CC=C43
InChI Code
InChI=1S/C24H23NO/c1-3-8-17(2)25-16-22(21-11-6-7-12-23(21)25)24(26)20-14-13-18-9-4-5-10-19(18)15-20/h4-7,9-17H,3,8H2,1-2H3
InChI Key
KTHPRMCSIRQVGE-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2), 133-140 (2000).

2. Auwärter, V., Dresen, S., Weinmann, W., et al. “Spice” and other herbal blends: Harmless incense or cannabinoid designer drugs? Journal of Mass Spectrometry 44, 832-837 (2009).

3. Lindigkeit, R., Boehme, A., Eiserloh, I., et al. Spice: A never ending story? Forensic Science International 191, 58-63 (2009).

4. Uchiyama, N., Kikura-Hanajiri, R., Kawahara, N., et al. Identification of a cannabimimetic indole as a designer drug in a herbal product Forensic Toxicol. 27, 61-66 (2009).

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