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JWH 122 3-methylnaphthyl isomer

Item № 9001033
CAS № 1391052-25-7
Purity ≥98%
product image
                (CAS 1391052-25-7)

Formulation:  A solution in methanol

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $49.00 0.00
     5 mg $221.00 0.00
     10 mg $392.00 0.00

Pricing updated 2019-03-26. Prices are subject to change without notice.

Description

JWH 122 is a synthetic cannabinoid (CB) that displays high-affinities for both central cannabinoid (CB1) (Ki = 0.69 nM) and peripheral cannabinoid (CB2) (Ki = 1.2 nM) receptors.1,2 It has been detected in commercially-available herbal products.3 JWH 122 3-methylnaphthyl isomer differs from JWH 122 in that the methyl group is attached to the naphthyl rings at the 3, rather than the 4, position. The biological and toxicological properties of this compound have not been characterized. This product is intended for forensic purposes.

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Technical Information
Formal Name
(3-methylnaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone
CAS Number
1391052-25-7
Molecular Formula
C25H25NO
Formula Weight
355.5
Purity
≥98%
Formulation
A solution in methanol
λmax
222, 315 nm
SMILES
CCCCCN1C=C(C(C2=CC(C)=CC3=C2C=CC=C3)=O)C4=CC=CC=C41
InChI Code
InChI=1S/C25H25NO/c1-3-4-9-14-26-17-23(21-12-7-8-13-24(21)26)25(27)22-16-18(2)15-19-10-5-6-11-20(19)22/h5-8,10-13,15-17H,3-4,9,14H2,1-2H3
InChI Key
AWAISCZQPNYSRY-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Huffman, J.W., Mabon, R., Wu, M.J., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor Bioorganic & Medicinal Chemistry 11, 539-549 (2003).

2. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists Bioorg. Med. Chem. 13, 89-112 (2005).

3. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3), 109-115 (2011).

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