An Analytical Reference Standard
Related Products
Unlabeled Version(s)
9001142Norsufentanil
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Norsufentanil-d3

Item No. 9001143

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • R 30451-d3
Technical Information
Formal Name
N-[4-(methoxy-d3-methyl)-4-piperidinyl]-N-phenyl-propanamide
CAS Number
1204688-16-3
Molecular Formula
C16H21D3N2O2
Formula Weight
279.4
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 0.16 mg/ml
SMILES
O=C(CC)N(C1=CC=CC=C1)C2(COC([2H])([2H])[2H])CCNCC2
InChi Code
InChI=1S/C16H24N2O2/c1-3-15(19)18(14-7-5-4-6-8-14)16(13-20-2)9-11-17-12-10-16/h4-8,17H,3,9-13H2,1-2H3/i2D3
InChi Key
ULOZGJWEIWAWML-BMSJAHLVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $103

    Add

    1 mg

    $194

    Add

    5 mg

    $801

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    Norsufentanil-d3 contains three deuterium atoms. It is intended for use as an internal standard for the quantification of norsufentanil by GC- or LC-mass spectrometry. Sufentanil is a powerful synthetic opioid analgesic that is used in anesthesia and palliative care.1,2,3 Norsufentanil is a metabolite of sufentanil, produced by oxidative N-dealkylation in the liver by cytochrome P450 isoforms.4 The physiological and toxicological properties of this compound are unknown. This product is intended for forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bovill, J.G., Sebel, P.S., and Stanley, T.H. Opioid analgesics in anesthesia: With special reference to their use in cardiovascular anesthesia. Anesthesiology 61(6), 731-755 (1984).

    2. Hodgson, P.S., Neal, J.M., Pollock, J.E., et al. The neurotoxicity of drugs given intrathecally (spinal). Anesth. Analg. 88(4), 797-809 (1999).

    3. King, S., Forbes, K., Hanks, G.W., et al. A systematic review of the use of opioid medication for those with moderate to severe cancer pain and renal impirment: A European Palliative Care Research Collaborative opioid guidelines project. Palliat. Med. 25(5), 525-552 (2011).

    4. Tateishi, T., Krivoruk, Y., Ueng, Y.F., et al. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. Anesth. Analg. 82(1), 167-172 (1996).