An ester version of the free acid
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Nervonic Acid methyl ester

Item No. 9001351

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
15Z-tetracosenoic acid, methyl ester
CAS Number
2733-88-2
Synonyms
  • Methyl Nervonate
  • SFE 25:1
Molecular Formula
C25H48O2
Formula Weight
380.7
Purity
≥98%
Formulation (Request formulation change)
A 100 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 100 mg/ml
SMILES
CCCCCCCC/C=C\CCCCCCCCCCCCCC(OC)=O
InChi Code
InChI=1S/C25H48O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25(26)27-2/h10-11H,3-9,12-24H2,1-2H3/b11-10-
InChi Key
AINIZSBLAFHZCP-KHPPLWFESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 mg

    $63

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    100 mg

    $94

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    500 mg

    $423

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    Product Description

    Nervonic acid (24:1n-9) (Item No. 13940) is a very long chain fatty acid produced by elongation of oleic acid (18:1n-9) (Item No. 90260) and derived from erucic acid (22:1n-9) (Item No. 90175).1 It is enriched in nervous tissue and is particularly abundant in sphingolipids, such as sphingomyelin in the myelin sheath of nerve fibers.2 Nervonic acid is poorly produced in demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, suggesting that dietary supplementation may be beneficial.3 Nervonic acid methyl ester is an ester version of the free acid which may be more suitable for the formulation of fatty acid-containing diets and dietary supplements.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Taylor, D.C., Francis, T., Guo, Y., et al. Molecular cloning and characterization of a KCS gene from Cardamine graeca and its heterologous expression in Brassica oilseeds to engineer high nervonic acid oils for potential medical and industrial use. Plant Biotechnol. J. 7(9), 925-938 (2009).

    2. Hirvisalo, E.L., and Renkonen, O. Composition of human serum sphingomyelins. J. Lipid Res. 11(1), 54-59 (1970).

    3. Sargent, J.R., Coupland, K., and Wilson, R. Nervonic acid and demyelinating disease. Med. Hypotheses 42(4), 237-242 (1994).