An internal standard for the quantification of PGE2-EA
Related Products
Unlabeled Version(s)
14012Prostaglandin E2 Ethanolamide
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Prostaglandin E2 Ethanolamide-d4

Item No. 9001412

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide-d4
Synonyms
  • Dinoprostone Ethanolamide-d4
  • PGE2-EA-d4
  • Prostamide E2-d4
Molecular Formula
C22H33D4NO5
Formula Weight
399.6
Purity
≥99% deuterated forms (d1-d4)
Formulation
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: > 100mg/mlDMSO: > 100mg/mlEthanol: > 100mg/mlPBS (pH 7.2): 12 mg/ml
SMILES
O=C1[C@H](C/C=C\CCCC(NC([2H])([2H])C([2H])([2H])O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C22H37NO5/c1-2-3-6-9-17(25)12-13-19-18(20(26)16-21(19)27)10-7-4-5-8-11-22(28)23-14-15-24/h4,7,12-13,17-19,21,24-25,27H,2-3,5-6,8-11,14-16H2,1H3,(H,23,28)/b7-4-,13-12+/t17-,18+,19+,21+/m0/s1/i14D2,15D2
InChi Key
GKKWUSPPIQURFM-GSBTUTNTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    25 µg

    $75

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    50 µg

    $134

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    100 µg

    $222

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    Product Description

    Prostaglandin E2 ethanolamide (PGE2-EA)-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of PGE2-EA by GC- or LC-mass spectrometry. PGE2-EA is an analog of PGE2 with improved water solubility and stability. PGE2-EA acts as an agonist with all four known EP receptor subtypes, but with an affinity that is significantly reduced compared to PGE2.1 PGE2 -EA is produced by HCA-7 cells treated with arachidonoyl ethanolamide.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ross, R.A., Craib, S.J., Stevenson, L.A., et al. Pharmacological characterization of the anandamide cyclooxygenase metabolite: Prostaglandin E2 ethanolamide. J. Pharmacol. Exp. Ther. 301(3), 900-907 (2002).

    2. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. The Journal of Biological Chemisty 277(47), 44877-44885 (2002).